IFNA1 and systemic lupus erythematosus: For example, LMNA proteins, encoded by the LMNA gene, are linked to SLE pathogenesis; autoantibodies against lamin C are associated with systemic secondary vasculitis in SLE [46], and LMNA mRNA expression has been identified as a specific antiviral response to type I interferon (IFN) activation in chilblain lupus erythematosus [47].