Among the subjects included in the analysis, 53 had BRCA1 and 94 had BRCA2. A total of 66 contralateral breast cancers (CBCs) were reported; 51(6.5%) of the 788 women without BRCA compared to 15 (10%) of the 147 women with pathogenic BRCA1/2 variants. Here, BRCA1 is linked to breast carcinoma.