MAP2K1 and non-small cell lung carcinoma: For the rMuPDGF-BB-induced murine KRASG12C-mutant NSCLC cell line LLC, the phosphorylation of SRC, C-RAF, MEK1/2 and the expressions of Ras, JUNB, FOSB and PD-L1 were also obviously suppressed by increasing concentrations of tricin.