Studies have shown that CD62L+ cells can be used to reveal the dynamics of disease activity and assess T cell-mediated autoimmune and immunodeficient children’s response to drug interventions; CD62L+ T cells were inversely associated with the severity of transcription factor P3 (Forkhead box P3, Foxp3) deficiency autoimmune disease (36). The gene discussed is FOXP3; the disease is hyperinsulinemic hypoglycemia, familial, 4.