The distinction between viral effects on exploring novel objects and time spent in the more anxiety-provoking center of the open field is consistent with the preferential exploring of familiar objects without changes in exploratory behavior seen in mutant mice lacking RICH2 (RhoSAP: RhoGAP synapse-associated protein), a phenotype that relates to developmental disorders such as autism spectrum disorder (Sarowar et al., 2017). The gene discussed is ARHGAP1; the disease is Anxiety.