KRAS and pancreatic ductal adenocarcinoma: In pancreatic ductal adenocarcinoma (PDAC), activated kirsten rat sarcoma viral oncogene homolog (KRAS) upregulates iron‐sulfur clusters 2 expression and promotes α‐KG catabolism in mice, which leads to suppression of TET3 and DNA 5mC‐dependent PDAC cell proliferation [279].