Examples include the aggregation of tau protein or amyloid‐β (Aβ) in AD, aggregation of RBPs TDP‐43 or fused in sarcoma (FUS) in ALS and FTD, α‐Synuclein (α‐Syn) aggregation and amyloid formation in PD and polyglutamine (polyQ) aggregation in HD [13, 119]. The gene discussed is MAPT; the disease is frontotemporal dementia.