Examples include the aggregation of tau protein or amyloid‐β (Aβ) in AD, aggregation of RBPs TDP‐43 or fused in sarcoma (FUS) in ALS and FTD, α‐Synuclein (α‐Syn) aggregation and amyloid formation in PD and polyglutamine (polyQ) aggregation in HD [13, 119]. Here, TARDBP is linked to amyotrophic lateral sclerosis.