Examples include the aggregation of tau protein or amyloid‐β (Aβ) in AD, aggregation of RBPs TDP‐43 or fused in sarcoma (FUS) in ALS and FTD, α‐Synuclein (α‐Syn) aggregation and amyloid formation in PD and polyglutamine (polyQ) aggregation in HD [13, 119]. The gene discussed is FUS; the disease is Huntington disease.