As a key transcriptional regulator of the TGF‐β pathway, lactylated Snail1 enhances Tgfb1/Smad2 signaling transduction, upregulates TGF‐β expression, and promotes endothelial‐to‐mesenchymal transition (EndoMT), ultimately exacerbating myocardial fibrosis and cardiac dysfunction [109]. Here, TGFB1 is linked to Myocardial fibrosis.