The expression of PD-L1 by tumors further aids in immune evasion, a phenomenon seen in various solid tumors (such as lung and breast cancers) and hematolymphoid malignancies, including angioimmunoblastic T-cell lymphoma, follicular lymphoma (FL), DLBCL, primary mediastinal B-cell lymphoma (PMBCL), and classical Hodgkin lymphoma (cHL), especially the nodular sclerosis subtype. The gene discussed is CD274; the disease is classic Hodgkin lymphoma.