Additionally, CRM12-infected colons did not trigger expansion of CD4+, CD8+, and total T cells (S4B-F), plasmacytoid dendritic cells (pDCs), conventional dendritic cells (cDCs), monocytes, and inflammatory Ly6C+ monocytes (iMonocytes) which were observed in CRWT infection (Figure 5(i–l), and S6A-C). Here, CD4 is linked to infection.