explored the potential of polymeric chitosan nanoparticles to improve the absorption and the oral bioavailability of Astragalus polysaccharides (APS), which are known for their TLR4 inhibitory activity, against cecal ligation and puncture (CLP)‐induced sepsis and myocardial injury.[90] Their results revealed that treatment with APS nanoparticles maintained the cell viability and cell morphology and exerted anti‐apoptotic effects in an in vitro model of LPS‐treated H9c2 cells. Here, TLR4 is linked to Sepsis.