In an in vivo model of methicillin‐resistant Staphylococcus aureus (MRSA)‐induced sepsis, the nanocarrier significantly reduced the MRSA burden in blood and various organs and decreased the plasma levels of inflammatory markers, including IL‐6 and TNF‐alpha and IL‐1β.[102] Overall, this system represents a potentially precise approach for targeted antibiotic therapy. The gene discussed is TNF; the disease is Sepsis.