NF‐κB activation results in the production and release of various pro‐inflammatory cytokines, such as tumor necrosis factor‐alpha (TNF‐α), interleukin‐1 alpha (IL‐1α), IL‐6, and IL‐8, which contribute to the cytokine storm and systemic inflammation during sepsis.[43]. This evidence concerns the gene NFKB1 and Sepsis.