POMC and obstructive sleep apnea syndrome: ACTH at 0am (F = 7.464, df = 2, P = 0.001, η2 = 0.064) and DCS (F = 3.081, df = 2, P = 0.048, η2 = 0.027) demonstrated significant effects of OSA severity, and no significant effects were observed for cortisol or ACTH measured at 8 AM.