Although there is currently no research related to TIGAR and cataracts, owing to the characteristics of cataract patients’ lenses, such as increased ROS formation, increased lipid peroxidation, and accumulation of redox-active iron in cells, it is probable that TIGAR plays a significant role in ROS production, lipid peroxidation, and ferroptosis in the lenses of cataract patients. Here, TIGAR is linked to cataract.