In the cross-sectional study by Karimi et al., there was no association among EcoR1 polymorphism (E-/E + and E−/E−, E+/E+) and Ins/Del polymorphism (Ins/Del, Del/Del, Ins/Ins) with hs.CRP, SOD, and TAC in 700 patients with T2DM [40]. This evidence concerns the gene SOD1 and type 2 diabetes mellitus.