In humans, MHC also has the name HLA (human leukocyte antigen), and MHC class I has three classical subtypes, HLA-A, HLA-B, and HLA-C.61 In this study, it was shown that all of the three subtypes of human MHC class I (e.g. HLA-A, HLA-B, and HLA-C) were enhanced by IFN-γ with the inhibition of miR-4319 and promotion of NLRC5 expression in SKBR3 breast cancer cells. The gene discussed is HLA-C; the disease is breast cancer.