IFNG and breast carcinoma: It was shown that, in SKBR3 breast cancer cells, after 24-h treatment with IFN-γ, the STAT1 and phosphorylated STAT1 (p-STAT1) were dose dependently increased in the groups treated with different concentrations of IFN-γ compared with the control group with statistical significance (p < .05) (Figure 7).