Of note, Brazilin prominently activates the STING pathway in NSCLC, triggering the expression of C‐X‐C motif chemokine ligand 10 (CXCL10), C‐X‐C Motif Chemokine Ligand 9 (CXCL9) and C‐C motif chemokine ligand 5 (CCL5), potentially assisting in overcoming immunotherapy resistance. The gene discussed is CXCL9; the disease is non-small cell lung carcinoma.