In our finding, CKD are positive correlated with effect T cell panel (CD28 + CD45RA + CD8 + T cell %, CD39 + CD8 + T cell Absolute Count, CD45RA + CD8 + T cell %T cell, CD28 + CD45RA + CD8dim T cell %T cel) and myeloid panel. The gene discussed is CD28; the disease is chronic kidney disease.