Previous research has also demonstrated that miR-383 protects against propofol-induced cognitive impairment by preventing hippocampal neuron apoptosis and the dysregulation of associated signalling pathways54.Furthermore, it has been shown that in brain tumours, such as gliomas, SV2B expression can influence tumour behaviour by affecting synaptic and neuronal environments33.​Thus, we could hypothesise that miR-383 plays a significant role in brain and synaptic functions, hence its involvement in learning and its direct SV2B gene target. Here, SV2B is linked to central nervous system cancer.