CXCL8 and osteosarcoma: While this study similarly explored the effects of cytokines on radiosensitization, our approach differs in that the increase of exogenous CXCL8 was inspired by Jiang et al.69, who used CXCL8 to stimulate the human osteosarcoma cell line MG-63, analyzing its effects on invasion, proliferation, apoptosis, and associated signaling pathways.