KL and acute kidney injury: This study aimed to investigate the potential of serum Klotho protein levels as a diagnostic and prognostic marker for AKI in TBI patients.The results showed that serum Klotho level 177.3 (165.43,195.07) (pg/ml) was elevated in patients with traumatic brain injury as compared to normal group 134.8(125.6,138.9) (pg/ml) .