Notably, the determined optimal cut-off for standard ADC of 0.0013 exhibited a sensitivity of 89.7% and specificity of 52.3% for predicting Ki-67 expression.Comparable research conducted by Zhang et al. involving 41 soft tissue sarcoma patients to evaluate standard ADC for predicting Ki-67 expression demonstrated a corresponding cut-off of 0.001305, yielding a sensitivity of 77.8% and specificity of 69.6%.17 The increase in Ki-67 expression is indicative of heightened tumor cell proliferation, leading to denser cellular arrangements and reduced extracellular space. The gene discussed is MKI67; the disease is soft tissue sarcoma.