EIF4A1 and head and neck squamous cell carcinoma: Similarly, DDX3X, an RNA helicase in the same family as EIF4A1, was more frequently mutated in EBV-positive HNSCC (p = 0.044), as previously reported141, and a similar trend was observed in BL and CC, though not statistically significant (Supplementary Fig. S14 and Supplementary Data 14).