Among our ACC cell-line derived xenografts, CU-ACC1 had lower surface ABCB1 expression than H295R (Supplementary Fig. 8A), which could at least partially explain the long-term tumor control with ADCT-701 treatment in CU-ACC1 but not H295R tumors (Fig. 3A). The gene discussed is ABCB1; the disease is adrenal cortex carcinoma.