Current scientific evidence suggests that insulin is not only crucial for the regulation of glucose metabolism but also plays a vital role in numerous processes related to cognitive functioning by modulating neuronal glucose uptake, synaptic plasticity, memory formation, and neurotransmitter regulation8–11 Moreover, pathological alterations in glucose homeostasis, insulin resistance, and diabetes may impair normal brain function through various pathophysiological mechanisms12. The gene discussed is INS; the disease is diabetes mellitus.