Most of the 313 new disease links belonged to the DisGeNET class neoplasms (n = 40; EGFR, ERBB2, KITLG, AREG) but also to immune diseases (n = 29; FAS), neurological diseases (n = 13; PNPLA6), and cardiovascular diseases (n = 13; CD163) (Fig. 10b, c). This evidence concerns the gene AREG and nervous system disorder.