Among the top 10 proteins sequentially ranked according to the fold change value of upregulated phosphorylation, 6 proteins (FRYL, SYNRG, SRRM2, HSP27, RAPH1 and ERBIN) contained the canonical PKA phosphorylation motif RXXS, but only the phosphorylation of HSP27 has been widely reported in tumor biology. Here, SYNRG is linked to neoplasm.