At the CALCRL/TFPI locus, a genetic variant rs840616 has been associated with CAD risks (\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\:\beta\:$$\end{document}=0.0402) in European populations24. The gene discussed is TFPI; the disease is coronary artery disorder.