ERBB2 and neoplasm: When comparing the AR/PGR ratio across all surrogate subtypes (Supplementary table 3), the results indicate that tumor tissues from patients classified as Luminal B (Odds ratio: 1.645; 95% CI: 1.001–2.703; p = 0.05) and HER2-enriched (Odds ratio: 2.581; 95% CI: 1.104–6.032; p = 0.029) are significantly associated with AR/PGR ≥ 1.54, compared to tissues from patients classified as Luminal A (Fig. 3).