PGR and breast cancer: We conducted multiple analyses on 58 transcriptomic data sets of gene microarrays, where it was observed that high levels of AR gene expression relative to ESR1 and PGR (≥ 2.0 and ≥ 1.54, respectively) may be associated with BC patients having poorer clinical features, as well as Luminal B, and HER2-enriched subtypes.