Overexpression of nine genes, including HJURP, COMP, KRTAP5-1, VGF, SSTR1, LINC01612, NAALADL2-AS2, AMH, and ARHGDIG, was significantly associated with poorer prognosis in PCa patients (p < 0.05, Fig. 2C-G, S1 C-1F). Here, COMP is linked to posterior cortical atrophy.