Among patients with shorter infections, most variants were at low (5%–20%) frequencies, and certain sites, such as 4329 (NSP3: I537T), 7507 (NSP3: K1596N), 17190 (NSP13: V318A), and 27750 (ORF7a: K119K), occurred sporadically. The gene discussed is SH2D3C; the disease is infection.