In GBM-bearing mice treated with anti-Lair1 antibody, we observed a moderate reduction in collagen deposition compared with Lair1–/– mice, which could have been due to the delayed timing of sample collection (63 days after the final dose of anti-Lair1 antibody) (Supplemental Figure 10, A and B). Here, LAIR1 is linked to glioblastoma.