We found that in primary glioblastoma multiforme (GBM), LAIR1 is positively associated with other immune checkpoints, such as PDCD1 (aka PD-1), CD274 (aka PD-L1), PDCD1LG2 (aka PD-L2), CTLA4, and TIGIT in primary GBM using The Cancer Genome Atlas (TCGA) dataset (Supplemental Figure 1A; supplemental material available online with this article; https://doi.org/10.1172/JCI184043DS1). The gene discussed is CD274; the disease is glioblastoma.