In alignment with the trends in cholesterol, GRALT/ALT women displayed an increased odds ratio of 1.34 (95% CI: 1.02–1.76; P = 0.0092) for hypercholesterolemia (total cholesterol >240 mg/dL) and 2.37 (95% CI: 1.05–5.9; P = 0.01) for death due to cardiovascular diseases, compared with GRref/ref women (Figure 1, C and D). The gene discussed is GPT; the disease is familial hypercholesterolemia.