Reported in a recent preprint, [212Pb]Pb-Pentixather increased survival in murine CXCR4 tumour models, though the risk of myelotoxicity clinically was noted due to the greater affinity of Pentixather for the human CXCR4 isoform expressed on hematopoietic stem cells (Christensen et al. 2024). The gene discussed is CXCR4; the disease is neoplasm.