Notably, elevated ZWINT expression was consistently observed across all major breast cancer histological subtypes: infiltrating ductal carcinoma (Q1–Q3: 27.55–62.183, n = 784, P < 1.0E−12), infiltrating lobular carcinoma (Q1–Q3: 17.401–40.013, n = 203, P < 1.0E−12), infiltrating ductal and lobular carcinoma (Q1–Q3: 25.683–48.996, n = 29, P = 7.961E−11), mucinous carcinoma (Q1–Q3: 20.983–35.436, n = 17, P = 3.401E−03), medullary carcinoma (Q1–Q3: 57.865–76.304, n = 6, P = 8.365E−04) (Fig. 1c), compared with the normal tissue (Q1–Q3: 4.732–9.895, n = 114). Here, ZWINT is linked to breast cancer.