CD274 and neoplasm: In line with these results, the transcriptome of in vivo–treated 4T1 tumor cells considerably changed after treatment with the CDDP-Eri combination, showing the induction of the expression of numerous proinflammatory or chemoattractant cytokine genes, genes involved in the type I IFN response or CTL/Th1 polarization, genes involved in antigenic presentation, as well as genes involved in PD-L1 (Cd274) induction (Figure 2, D and E).