POC1B and short stature-onychodysplasia-facial dysmorphism-hypotrichosis syndrome: Alongside POC5, 2 other proteins, POC1A (HGNC:24488) and POC1B (HGNC:30836), localize to the distal centriole and likely also play a role in centriolar elongation.20 Biallelic variants in POC1A cause short stature, onychodysplasia, facial dysmorphisms, and hypotrichosis (SOFT) syndrome (OMIM 614813).