Although lung cancer is not among the cancers traditionally thought of as being hormone sensitive, both male (androgens, e.g. testosterone) and female (e.g. estrogen) sex hormones have been reported to influence the pathophysiology of lung cancer (10, 11) and lung cancer cells have been reported to produce estrogen through the action of aromatase activity (12). This evidence concerns the gene CYP19A1 and lung carcinoma.