Another study shows that potassium channel, subfamily K, member 1 gene (KCNK1) enhances glycolysis in breast cancer cells by interacting with and activating LDHA, which subsequently induces the expression of ZW10 interactor (ZWINT), Anillin, actin binding protein (ANLN), and LDHA through H3K18la modification, promoting proliferation, invasion, and metastasis (110). This evidence concerns the gene LDHA and breast cancer.