In some studies, certain MAPT variants associated with an increased risk of tauopathies, likely due to increased MAPT expression (Tanahashi et al., 2004; Laws et al., 2007; Myers et al., 2007; Russ et al., 2001; Baker et al., 2000; Bullido et al., 2000; Clark et al., 2003; Kwok et al., 2004). This evidence concerns the gene MAPT and tauopathy.