AIFM2 and cancer: Studies have demonstrated that NAT10 restrains ferroptosis by stabilizing the mRNA of the ferroptosis suppressor protein 1 (FSP1) [155] and solute carrier family 7 member 11 (SLC7 A11) via ac4C modification, preventing oxidative stress that triggers phospholipid oxidation to initiate ferroptosis, thereby promoting the progression of cancer [94, 109].