ATAC-sequencing analysis of PTCs from an ischemia-reperfusion injury-induced renal fibrosis mouse model (GSE197815) revealed increased chromatin accessibility in the promoter regions of POSTN, FSTL1, and FSCN1 genes during the progression of renal fibrosis (Appendix Fig. S18B). The gene discussed is FSTL1; the disease is renal fibrosis.