Moreover, SH-BC-893 but not PPZ reduced nuclear levels of the TNPO1 cargo and cancer-associated protein hnRNPA1 (Fig. 3B,C; Appendix Fig. S7B) (Möller et al, 2020; Twyffels et al, 2014; Roy et al, 2017). The gene discussed is TNPO1; the disease is breast cancer.