NFKB1 and pulmonary arterial hypertension: In the field of advanced delivery methods, nanoparticle-mediated delivery of NF-κB decoy into lungs has shown promise in ameliorating MCT-PAH.204 Among natural compounds, Srolo Bzhtang,214Paeoniflorin,414 Resveratrol437 have demonstrated efficacy in attenuating PAH through modulation of the NF-κB signaling pathway.