PLOD1 and polycystic ovary syndrome: A recent 308 multicenter RCT demonstrated that PCOS patients exhibited broader LH thresholds (0.8–6.2 IU/L) compared to normo-ovulatory controls, suggesting enhanced follicular resilience to LH fluctuations in this population.[45] The results of the present study suggest that in patients with PCOS, the basic serum LH level was generally higher and the serum LH level in the late follicular phase was slightly higher than those of benefited oocyte growth and development for COS with pretreatment.