In the field of inflammation, scRNA-seq has been used to draw a map of epithelial cell subsets in an acute chemical lung injury model, and new Sox9-positive type II alveolar epithelial cell subsets with stem cell differentiation potential have been identified that are recruited to the injured epithelial barrier and participate in epithelial cell regeneration and tissue repair.[20] Neutrophils play a key role in the occurrence and development of ARDS. Here, SOX9 is linked to acute respiratory distress syndrome.