These elements collectively manifest as stellate hypointensity on HBP, surrounded by hyperintense parenchyma with preserved OATP1B3 function.[5] Conversely, HCCs rarely develop true central scars—a dichotomy exploited by our model, where scar absence emerged as a potent HCC indicator (OR = 0.04). This evidence concerns the gene SLCO1B3 and hepatocellular carcinoma.