Although abnormalities in various immune cells are critical contributors to autoimmune destruction in uveitis, T cells, especially effector T cells (e.g., Th1 and Th17 cells) and Treg are considered pivotal in the pathogenesis of uveitis and its classic animal model, EAU.[31, 32] Solely transfer of autoreactive CD4+ T cells can induce EAU in naïve mice,[33, 34] a capability not possessed by other cell types. Here, CD4 is linked to uveitis.