In addition, G protein signal transduction regulator 2 (Rgs2) serves as a regulator of G protein‐coupled receptors, which could influence the targeted migration of immune cells toward the tumor site and fully activate, as well as secretion of cytokines, thereby enhancing the synergistic tumor‐killing ability.[34] Research indicates that Rgs2 is integral to the pathophysiology of various tumors, with its expression levels in colorectal cancer being strongly correlated with patients’ prognosis. This evidence concerns the gene RGS2 and neoplasm.