In addition, G protein signal transduction regulator 2 (Rgs2) serves as a regulator of G protein‐coupled receptors, which could influence the targeted migration of immune cells toward the tumor site and fully activate, as well as secretion of cytokines, thereby enhancing the synergistic tumor‐killing ability.[34] Research indicates that Rgs2 is integral to the pathophysiology of various tumors, with its expression levels in colorectal cancer being strongly correlated with patients’ prognosis. The gene discussed is RGS2; the disease is colorectal cancer.