Additionally, Rgs2+CD8+ T cells also exhibit high expression of various chemokines including CCL4 and CXCL12, which may facilitate the recruitment of B cells to tumor sites and subsequently engage in interactions through the MIF/CD74 pathway to enhance activation and proliferation, thereby augmenting the anti‐tumor immune response to augment the anti‐tumor immune response. The gene discussed is MIF; the disease is neoplasm.