To elucidate the potential mechanisms of gcFGF8a induction, we screened inhibitors targeting pathways classically activated by bacterial infection, including Tofacitinib (JAK), LY294002 (PI3K), IWR‐1 (Wnt), SB431542 (TGF‐β), and BAY11‐7082 (NF‐κB). This evidence concerns the gene TGFB1 and bacterial infectious disease.