SAA3P and neoplasm: Indole-3-lactic acid derived from Lactobacillus plantarum has been shown to ameliorate tumor growth, intestinal inflammation, and gut dysbiosis by improving tumor-infiltrating CD8+ T cell activity by decreasing their cholesterol levels through the downregulation of Serum amyloid A3 (Saa3), a key gene involved in cholesterol metabolism [98].